Dr. Mark DiStefano, MD
Board Certified Hair Restoration Surgeon
Worcester, Massachusetts
● Taking New Patients
3.55(9 ratings)
About
Dr. Mark DiStefano, MD is a Board Certified Hair Restoration Surgeon based in Worcester, Massachusetts. His practice specializes in female hair loss, with over a decade of experience across locations in Massachusetts and New York. He views hair loss as a medical condition requiring accurate diagnosis, not a one-size-fits-all approach. His practice emphasizes investigation over guessing, utilizing tools like Trichoscopy and bloodwork to ensure a treatment plan designed for the specific type of hair loss.
Dr. DiStefano offers a distinct approach to PRP, called Optimal Platelet Concentration Therapy (OPC). This involves measuring a patient's platelet count on the day of treatment and adjusting the PRP to an optimal range, aiming for personalized results. This method is administered without needles or scalp trauma. While excited about the science of exosomes, Dr. DiStefano's practice awaits long-term safety and efficacy data before recommending them. They are committed to listening to women, providing answers, and creating individualized treatment plans, recognizing the emotional impact of hair loss.
Connect with Dr. Mark DiStefano on Social Media
Specialties
- Board Certified Hair Restoration Surgeon
Procedures & Services
Select a service to schedule an appointment · each is approximately 60 minutes
Average Cost of Surgery
Healthcare costs shouldn't be a mystery. Below, you'll find crowdsourced data on the actual costs of surgeries performed by Dr. Mark DiStefano, submitted anonymously by the patient community. Use this as a guide to better anticipate your own expenses. Please note that final costs can vary based on your specific medical needs.
Hair Loss Treatment
$2,500
Eyebrow Transplant
$4,500
Hair Transplant
$6,400
Fue Hair Transplant
$7,295
Help us keep this data current and accurate. If you've had a procedure with Dr. Mark DiStefano, please take a moment to contribute your cost information.
Questions, Answers, and Information Directly from Dr. Mark DiStefano
Sourced directly from Dr. Mark DiStefano's social posts and replies.
What is Dr. DiStefano's approach to PRP (Platelet-Rich Plasma) therapy?
Dr. DiStefano offers a specialized 'Painless PRP' method, also known as Optimal Platelet Concentration Therapy (OPC). This advanced approach delivers the body’s own growth factors beneath the scalp without needles or injections, causing no scalp trauma. It activates hair follicles and supports real hair regrowth for the right patient. Unlike standard PRP, the practice measures the patient's platelet count on the day of treatment and adjusts the PRP to an optimal range (approximately 1.4 to 1.6 billion platelets per milliliter) to create a personalized and targeted treatment plan, as more is not always better. This avoids a one-size-fits-all protocol, which they consider an unreliable 'guess'. Patients considering PRP elsewhere are advised to ask if their platelet count is measured on the day of treatment.
What should I know about hair shedding while taking GLP-1 medication?
Excessive shedding experienced while taking GLP-1 medication is often telogen effluvium, which can be triggered by rapid weight loss, physical stress, or nutritional deficiencies. This type of shedding is often reversible once the underlying triggers are addressed and weight stabilizes. The practice recommends getting comprehensive blood work, evaluating nutrition and protein intake, and scheduling a scalp evaluation and trichoscopy with a female hair loss specialist to get an accurate diagnosis. It's important not to assume the cause, as some women may have another form of hair loss occurring simultaneously.
What is Dr. DiStefano's philosophy on diagnosing hair loss?
Dr. DiStefano emphasizes that hair loss is not random and requires an accurate diagnosis before any treatment begins. The practice believes in investigating rather than guessing the cause of hair loss, as different types require different treatment plans. They utilize comprehensive diagnostic tools like Trichoscopy readings, bloodwork (checking ferritin, thyroid, vitamin D, hormones), and sometimes biopsy to determine if hair loss is scarring or non-scarring, and to uncover underlying contributors. A test is considered valuable if its result changes the treatment plan. The goal is a personalized treatment plan based on individual diagnosis, medical history, and biology, rather than a one-size-fits-all approach. They advise against delaying diagnosis, as early intervention can preserve existing hair and improve results.
What is Dr. DiStefano's stance on Exosome therapy for hair loss?
While the science behind exosomes is exciting and early findings are encouraging, Dr. DiStefano's practice currently does not recommend exosome therapy to patients. They emphasize that 'promising is not the same as proven,' noting that there are no FDA-approved exosome products, human evidence for hair loss is still limited, and products, sources, processing methods, and dosing are not standardized. The practice is closely watching the science and waiting for long-term safety and efficacy data before recommending them. Their philosophy is to avoid women wasting time or money chasing trends without first understanding the cause of their hair loss, though they acknowledge exosomes may have a place in hair restoration in the future.
What should patients know about Scarring Alopecia?
Scarring alopecia is a group of inflammatory hair loss conditions that can progressively damage and destroy hair follicles, potentially leading to permanent hair loss. Once a follicle has been completely destroyed and replaced by scar tissue, it cannot regrow hair. However, scarring does not always mean every follicle is lost. Early and accurate diagnosis is crucial because when viable follicles remain, the right treatment can help control inflammation, protect follicles from further damage, slow progression, and in some cases, support significant regrowth. Patients should seek investigation if they notice symptoms like thinning, changes along the hairline, widening areas of loss, scalp discomfort, itching, burning, or other unexplained changes, and not assume it's 'just thinning.' Treatment recommendations and outcomes depend on diagnosis, disease activity, and the extent of follicular damage.
What factors influence hair loss treatment outcomes?
Individual results vary. Treatment recommendations and outcomes depend significantly on the patient's specific diagnosis, the activity level of their hair loss condition, and the extent of existing follicular damage.
What is Dr. DiStefano's approach to Eyebrow Restoration?
Medi Tresse offers eyebrow restoration services through its trusted partners at Northeast Hair Restoration. The surgical team uses individual follicles from the patient's own scalp, carefully recreating the natural direction, angle, and shape of eyebrow growth for results that look and grow naturally. Every eyebrow transplant journey begins with a comprehensive consultation to assess candidacy and design a brow shape that complements the patient's unique features.
What are common indications for Eyebrow Transplantation?
Eyebrow transplantation may be an option for individuals who have experienced: overplucking, waxing, or threading; age- or hormone-related thinning; naturally sparse or uneven brows; hair loss following certain medical conditions or treatments; scarring or trauma; or unsatisfactory microblading or tattooing results.
What is Dr. DiStefano's view on genetic testing for hair loss?
Dr. DiStefano's practice believes that a genetic risk percentage for hair loss does not alter the treatment approach. Patients are examined, receive lab tests, and are treated based on their current scalp condition, irrespective of genetic risk. Genetics is considered only one of many possible causes of hair loss, and in their experience, most women have multiple concurrent factors contributing to their hair loss.
From Dr. Mark DiStefano's Instagram
@medi_tresse →Recent photos posted by @medi_tresse, Dr. Mark DiStefano's own Instagram account. Each image opens the original post on Instagram.
- @medi_tresseSep 2026
- @medi_tresseSep 2026
- @medi_tresseSep 2026
- @medi_tresseSep 2026
- @medi_tresseSep 2026
- @medi_tresseSep 2026
Images © Dr. Mark DiStefano / @medi_tresse, shown here with a link to the original post. If you are the account owner and want an image removed, contact [email protected].
Patient Experience
Dr. Mark DiStefano Review Summary
3.3
Dr. DiStefano's ratings are a bit mixed. He has a 3.6 rating on RealSelf and a 3.8 on Yelp, suggesting generally positive experiences. However, a 1/5 rating on Healthgrades brings his average down. It's worth looking into the specific reviews to get a better understanding of patient experiences.
Ratings from Other Platforms
Medi Tresse - Scarsdale
10 Winthrop St # 46, Worcester, Massachusetts
(774) 314-3900
Book a Service Consultation
Each service is approximately 60 minutes.
Insurance Information
Please contact Dr. Mark DiStefano's office directly for information about accepted insurance plans.
Phone: (774) 314-3900
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Location & Contact Information
Medi Tresse - Scarsdale
10 Winthrop St # 46
Worcester, Massachusetts 01604
Office Information
Phone: (774) 314-3900
Where does Dr. Mark DiStefano practice?
Doctor's Office
Medi Tresse - Scarsdale (Primary)
10 Winthrop St # 46, Worcester, Massachusetts 01604
(5 reviews)
Medi Tresse - Wellesley
10 Winthrop St # 46, Worcester, Massachusetts 01604
0Medi Tresse - Worcester
10 Winthrop St # 46, Worcester, Massachusetts 01604
0Hospital Affiliations
Mark is an excellent surgeon. He was always very attentive to the concerns of his clients. He has an excellent bedside manner and was sure to follow up with. DISTEFANO HAIR RESTORATION CENTER
Help improve our data. Confirm if Dr. Mark DiStefano is affiliated with Mark is an excellent surgeon. He was always very attentive to the concerns of his clients. He has an excellent bedside manner and was sure to follow up with. DISTEFANO HAIR RESTORATION CENTER.
DISTEFANO HAIR RESTORATION CENTER
Help improve our data. Confirm if Dr. Mark DiStefano is affiliated with DISTEFANO HAIR RESTORATION CENTER.
Education & Experience
Education
Medical Degree In 1979 From Georgetown University
Certifications & Licenses
Board Certified Hair Restoration Surgeon
Member Of The American Board Of Hair Restoration Surgery
Member Of The International Board Of Hair Restoration Surgery
Board Certified By The Abhrs
Fellow Of The Ishrs
Frequently Asked Questions
Can you make an appointment with Dr. Mark DiStefano online?
The provided information doesn't specify whether online appointments are available. It's best to contact Dr. DiStefano's office directly at (774) 314-3900 or check the Medi Tresse website. The practice offers comprehensive Female Hair Loss Evaluations with a Medi Tresse specialist. These one-on-one evaluations assess candidacy and design personalized treatment plans.
Does Dr. Mark DiStefano offer telehealth?
The provided information doesn't mention telehealth services. Contacting the office directly is recommended for the most accurate information.
What do patients have to say about Dr. Mark DiStefano?
Patient reviews range from positive experiences with LaserCap and FUT hair transplants to negative experiences with eyebrow transplants and overall poor results. One patient mentions a procedure being redone at no cost, suggesting responsiveness to patient concerns, but overall, experiences appear to vary.
What areas of care does Dr. Mark DiStefano cater to?
Dr. DiStefano specializes in hair restoration, including hair loss treatment, hair transplants (including FUE), and eyebrow transplants. He also has a background in emergency medicine. The practice views hair loss as a medical condition that requires an accurate diagnosis and a personalized treatment plan, rather than a one-size-fits-all approach. They are committed to listening to women who feel dismissed, providing answers when they feel uncertain, and creating treatment plans that are as individual as the women they care for, based on their unique diagnosis, medical history, and biology. The emotional impact of female hair loss is recognized as every bit as real as the physical changes.